Interleukin-17-producing γδ T (γδ 17) cells in inflammatory diseases
نویسندگان
چکیده
منابع مشابه
IL-17-producing γδ T cells enhance bone regeneration.
Immune responses are crucial not only for host defence against pathogens but also for tissue maintenance and repair after injury. Lymphocytes are involved in the healing process after tissue injury, including bone fracture and muscle damage. However, the specific immune cell subsets and mediators of healing are not entirely clear. Here we show that γδ T cells produce IL-17A, which promotes bone...
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Interleukin 17-producing γδ T (γδT17) cells have unconventional trafficking characteristics, residing in mucocutaneous tissues but also homing into inflamed tissues via circulation. Despite being fundamental to γδT17-driven early protective immunity and exacerbation of autoimmunity and cancer, migratory cues controlling γδT17 cell positioning in barrier tissues and recruitment to inflammatory s...
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ژورنال
عنوان ژورنال: Immunology
سال: 2018
ISSN: 0019-2805
DOI: 10.1111/imm.12993